Earth's greatest protectors-Superman, Batman, and Wonder Woman-have vanished. The cities of Metropolis and Gotham are overrun with criminal activity both on the streets and behind the closed doors of powerful corporations as villains take advantage of the absence of superheroes.

In their place stand the veteran and rookie heroes they inspired. From popular media personality Booster Gold and the enigmatic Question to the mysterious vigilante Batwoman and the secretive Supernova, these heroes are the only ones who can turn the tide against a vast conspiracy of evil determined to take control of the planet.

This is the story of one year without the world's greatest superheroes. Twelve months. 365 days. 52 weeks.